Pooled allogeneic faecal microbiota MaaT013 for steroid-resistant gastrointestinal acute graft-versus-host disease: a single-arm, multicentre phase 2 trialResearch in context

Summary: Background: Failure of gastrointestinal acute graft-versus-host disease (GI-aGvHD) to respond to steroid therapy is associated with limited further therapeutic options.We aimed to assess the safety and efficacy of the first-in-human use of the pooled allogeneic faecal microbiota, MaaT013, for the treatment of steroid-refractory GI-aGvHD.Me

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Clinical and Histologic Features Compared with AgNOR Count in Oral Leukoplakia, Erosive Lichen Planus, Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma

Nucleolar organizing regions (NORs) are loops of DNA containing ribosomal RNA genes.In human, they are located on the short arm of the five acrocentric of certain chromosomes.An increase in number Oversized Tee of AgNORs counts have been documented in some malignancies compared to their benign counter parts.The aim of the study was to correlate and

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